Primary splenic lymphoma presenting with ascites

Autor: Conor O'Riardon, Sarah Mahon, John B. Conneely, Oliver J. McAnena, N.A. Healy
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Rare Tumors, Vol 3, Iss 2, Pp e25-e25 (2011)
Rare Tumors
ISSN: 2036-3613
2036-3605
Popis: An 84 year-old gentleman presented with abdominal distension, anorexia and occasional epigastric pain over a four-week period. Blood parameters revealed a hypochromic microcytic anaemia. Both CT and US scan identified ascites and a mass in the left upper quadrant. An ascitic tap was performed identifying bloody ascites and the presence of reactive mesothelial cells on cytology. A subsequent laparotomy and splenectomy was performed. Histology of the resected spleen revealed a Grade 2 follicular lymphoma (Figure 2). The patient had an uneventful postoperative recovery and was well at 6 months follow up. The spleen is an organ with an important immunological function. Primary splenic involvement occurs in less than 1% of non-hodgkin’s lymphoma. Symptoms of primary splenic lymphoma (PSL) include pyrexia, weight-loss, night sweats, generalised weakness and left upper quadrant pain secondary to spleno - megaly. Ascites is a rare presenting feature of PSL. This report illustrates a case of primary splenic lymphoma which poses diagnostic challenges for the pathologist and clinician and ultimately requires definitive splenectomy to confirm a diagnosis. Figure 2Photograph of histology slide displaying the lymphoma at 10× magnification.
Databáze: OpenAIRE