Autor: |
Allen Cole Burks, Jason Akulian, Christina R. MacRosty, Sohini Ghosh, Adam Belanger, Muthu Sakthivel, Thad S. Benefield, Christina R. Inscoe, Otto Zhou, Jianping Lu, Yueh Z. Lee |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
J Thorac Dis |
ISSN: |
2072-1439 |
Popis: |
BACKGROUND: Screen detected and incidental pulmonary nodules are increasingly common. Current guidelines recommend tissue sampling of solid nodules >8 mm. Bronchoscopic biopsy poses the lowest risk but is paired with the lowest diagnostic yield when compared to CT-guided biopsy or surgery. A need exists for a safe, mobile, low radiation dose, intra-procedural method to localize biopsy instruments within target nodules. This retrospective cross sectional reader feasibility study evaluates the ability of clinicians to identify pulmonary nodules using a prototype carbon nanotube radiation enabled stationary digital chest tomosynthesis system. METHODS: Patients with pulmonary nodules on prior CT imaging were recruited and consented for imaging with stationary digital chest tomosynthesis. Five pulmonologists of varying training levels participated as readers. Following review of patient CT and a thoracic radiologist’s interpretation of nodule size and location the readers were tasked with interpreting the corresponding tomosynthesis scan to identify the same nodule found on CT. RESULTS: Fifty-five patients were scanned with stationary digital chest tomosynthesis. The median nodule size was 6 mm (IQR =4–13 mm). Twenty nodules (37%) were greater than 8 mm. The radiation entrance dose for s-DCT was 0.6 mGy. A significant difference in identification of nodules using s-DCT was seen for nodules |
Databáze: |
OpenAIRE |
Externí odkaz: |
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