Maternal and Fetal Exposure to Four Carcinogenic Environmental Metals
| Autor: | Huai Guan, Kazuhito Yokoyama, Xiao-Wei Li, Qiu-Juan Li, Fengyuan Piao, Lei Xu |
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| Rok vydání: | 2010 |
| Předmět: |
Time Factors
Health Toxicology and Mutagenesis chemistry.chemical_element Physiology Umbilical cord Toxicology Pregnancy medicine Humans Maternal-Fetal Exchange Carcinogen Cadmium Fetus Public Health Environmental and Occupational Health Environmental Exposure Environmental exposure medicine.disease Carcinogens Environmental medicine.anatomical_structure chemistry Metals Cord blood Environmental toxicology Environmental Pollutants Female |
| Zdroj: | Biomedical and Environmental Sciences. 23:458-465 |
| ISSN: | 0895-3988 |
| DOI: | 10.1016/s0895-3988(11)60008-1 |
| Popis: | Objective To examine maternal and fetal exposure levels to four carcinogenic metals, arsenic (As), cadmium (Cd), nickel (Ni), and beryllium (Be), and to investigate their environmental influences. Methods Metal concentrations in maternal and umbilical cord blood were measured by inductively coupled plasma–mass spectrometry (ICP-MS). Environmental factors that might play a role in exposure were analyzed using Mann–Whitney nonparametric U-tests and multiple linear regression. Results The concentrations of As, Cd, and Ni in umbilical cord blood (5.41, 0.87, and 139.54 μg/L) were significantly lower than those in maternal blood (6.91, 1.93, and 165.93 μg/L). There were significant positive correlations between the maternal and cord concentrations of each carcinogen. Our results showed that: (i) exposures to potentially harmful occupational factors during pregnancy were associated with high levels of maternal As, Cd, and Ni; (ii) living close to major transportation routes ( |
| Databáze: | OpenAIRE |
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