Incorporation ofcis-9,trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18:1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids
| Autor: | Graham C. Burdge, Jennifer J. Russell, R. Morgan, Sabine Tricon, Caroline E. Childs, Robert F. Grimble, Parveen Yaqoob, Phillip C. Calder, Kirsty E. Kliem, Emma L Jones, Christine M. Williams |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Animal feed Conjugated linoleic acid Medicine (miscellaneous) Vaccenic acid Blood lipids Oleic Acids Cattle feeding Eating chemistry.chemical_compound Double-Blind Method Isomerism Cheese Phosphatidylcholine Blood plasma Animals Humans Linoleic Acids Conjugated Food science Cross-Over Studies Nutrition and Dietetics Lipid metabolism Middle Aged Lipid Metabolism Animal Feed Diet Milk chemistry Food Fortified Butter Leukocytes Mononuclear Cattle Female Dairy Products |
| Zdroj: | British Journal of Nutrition. 94:237-243 |
| ISSN: | 1475-2662 0007-1145 |
| DOI: | 10.1079/bjn20051506 |
| Popis: | The present study investigated whether consuming dairy products naturally enriched incis-9,trans-11 (c9,t11) conjugated linoleic acid (CLA) by modification of cattle feed increases the concentration of this isomer in plasma and cellular lipids in healthy men. The study had a double-blind cross-over design. Subjects aged 34–60 years consumed dairy products available from food retailers for 1 week and then either control (0·17 gc9,t11 CLA/d; 0·31 gtrans-vaccenic acid (tVA)/d) or CLA-enriched (1·43 gc9,t11 CLA/d; 4·71 gtVA/d) dairy products for 6 weeks. After 7 weeks washout, this was repeated with the alternate products.c9,t11 CLA concentration in plasma lipids was lower after consuming the control products, which may reflect the two-fold greaterc9,t11 CLA content of the commercial products. Consuming the CLA-enriched dairy products increased thec9,t11 CLA concentration in plasma phosphatidylcholine (PC) (38%;P=0·035), triacylglycerol (TAG) (22%;PPPtVA concentration was greater in plasma PC (65%;P=0·035), TAG (98%;P=0·001) and PBMC (84%;P=0·004). Overall, the present study shows that consumption of naturally enriched dairy products in amounts similar to habitual intakes of these foods increased thec9,t11 CLA content of plasma and cellular lipids. |
| Databáze: | OpenAIRE |
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