Comparison of major protein antigens and protein profiles of Treponema pallidum and Treponema pertenue
| Autor: | J B Baseman, R W Thornburg |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Immunology
Radioimmunoassay Microbiology Bacterial Proteins Species Specificity Antigen medicine Animals Treponema Treponema pallidum Polyacrylamide gel electrophoresis Gel electrophoresis Antigens Bacterial biology Protein species biology.organism_classification medicine.disease Molecular biology Blot Infectious Diseases Electrophoresis Polyacrylamide Gel Parasitology Treponema pertenue Syphilis Rabbits Research Article |
| Zdroj: | Infection and Immunity. 42:623-627 |
| ISSN: | 1098-5522 0019-9567 |
| Popis: | The protein profiles of Treponema pallidum and Treponema pertenue, the causative agents of syphilis and yaws, respectively, were compared by one- and two-dimensional gel electrophoresis. One-dimensional gels showed essentially no differences in the protein patterns of these treponemes. On two-dimensional gels most radiolabeled protein species were shared; however, variations were noticed in several minor protein species. Antigenic comparison by radioimmunoprecipitation and Western blotting also demonstrated similarities between these spirochetes. However, lactoperoxidase-catalyzed iodination of T. pallidum and T. pertenue suggested differences in their surface proteins. |
| Databáze: | OpenAIRE |
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