Artificial tears potpourri: a literature review
| Autor: | Valliammai Muthappan, Majid Moshirfar, Luis Santiago-Caban, Samuel F. Passi, Kasey L. Pierson, Kamalani Hanamaikai |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pathology dysfunctional tear syndrome medicine.medical_treatment Alternative medicine Dysfunctional family Review Disease ophthalmic lubricant artificial tears liquid polyols dry eye Systane® Soothe® HPMC CMC Ophthalmology medicine tear osmolarity Lacrisert® Intensive care medicine tear film Blink® Ophthalmic lubricant Brand names business.industry Tear osmolarity eye diseases TBUT Clinical trial lipid layer Artificial tears ocular surface inflammatory disease polyvinyl alcohol Sjogren’s Syndrome GenTeal® Refresh® business |
| Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
| ISSN: | 1177-5483 |
| Popis: | Numerous brands and types of artificial tears are available on the market for the treatment of dysfunctional tear syndrome. Past literature has focused on comparing the components of these products on patient's clinical improvement. The wide array of products on the market presents challenges to both clinicians and patients when trying to choose between available tear replacement therapies. Different formulations affect patients based on etiology and severity of disease. In order to provide an unbiased comparison between available tear replacement therapies, we conducted a literature review of existing studies and National Institutes of Health clinical trials on commercially available, brand name artificial tears. Outcomes evaluated in each study, as well as the percent of patients showing clinical and symptomatic improvement, were analyzed. Fifty-one studies evaluating different brands of artificial tears, and their efficacy were identified. Out of the 51 studies, 18 were comparison studies testing brand name artificial tears directly against each other. Nearly all formulations of artificial tears provided significant benefit to patients with dysfunctional tear syndrome, but some proved superior to others. From the study data, a recommended treatment flowchart was derived. |
| Databáze: | OpenAIRE |
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