Development and Optimization of Osimertinib-loaded Biodegradable Polymeric Nanoparticles Enhance In-vitro Cytotoxicity in Mutant EGFR NSCLC Cell Models and In-vivo Tumor Reduction in H1975 Xenograft Mice Models
| Autor: | Sanjay Kumar K, Asha deepti Choppala |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Acrylamides
Aniline Compounds Indoles Lung Neoplasms Ecology Polymers Pharmaceutical Science General Medicine Aquatic Science ErbB Receptors Mice Pyrimidines Carcinoma Non-Small-Cell Lung Cell Line Tumor Mutation Drug Discovery Animals Heterografts Humans Nanoparticles Protein Kinase Inhibitors Agronomy and Crop Science Ecology Evolution Behavior and Systematics |
| Zdroj: | AAPS PharmSciTech. 23 |
| ISSN: | 1530-9932 |
| DOI: | 10.1208/s12249-022-02314-9 |
| Popis: | Osimertinib (OMB), a third-generation EGFR inhibitor, specifically and irreversibly inhibits EGFR |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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