Oxygen free radical scavenger enzyme polymorphisms in systemic sclerosis
| Autor: | Mary Gulumian, Paul Wordsworth, Sara E. Marshall, Neil A. Haldar, Mohammed Tikly, Ken I. Welsh |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Disease medicine.disease_cause Biochemistry Isozyme Scleroderma chemistry.chemical_compound Physiology (medical) medicine Humans Allele Alleles Glutathione Transferase chemistry.chemical_classification Polymorphism Genetic Scleroderma Systemic integumentary system Superoxide Dismutase Free Radical Scavengers Glutathione medicine.disease Phenotype Oxygen Enzyme chemistry Case-Control Studies Immunology Female Oxidative stress |
| Zdroj: | Free Radical Biology and Medicine. 36:1403-1407 |
| ISSN: | 0891-5849 |
| Popis: | We performed a case-control study of polymorphisms of glutathione S-transferase (GST) isoenzymes and manganese superoxide dismutase (MnSOD) in black South Africans with systemic sclerosis (SSc). The frequency of the GSTM1*B phenotype was significantly decreased in the overall SSc group compared with controls (OR=0.19, p(corr) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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