Rapid tests and transfusion safety in Niamey, Niger
| Autor: | Adelin Albert, D. Gossens, Nadia Dardenne, Catherine Gérard, M. Seydou, Z. Mayaki, Michel Moutschen, D. Sondag |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male HBsAg medicine.medical_specialty Time Factors Blood transfusion Adolescent Hepatitis C virus medicine.medical_treatment Human immunodeficiency virus (HIV) HIV Antibodies medicine.disease_cause Gastroenterology Donor Selection Young Adult Antigen Internal medicine medicine Humans Blood Transfusion Niger Aged Hematologic Tests Hepatitis B Surface Antigens biology business.industry Public Health Environmental and Occupational Health Hepatitis C Antibodies Middle Aged Hepatitis B medicine.disease Surgery Infectious Diseases Blood donor biology.protein Female Antibody business |
| Zdroj: | Médecine et Santé Tropicales. 27:95-100 |
| ISSN: | 2261-2211 2261-3684 |
| Popis: | To evaluate the virological safety of blood components provided by the Niamey blood transfusion center after undergoing rapid tests. Samples found negative with rapid tests (n = 222) were screened by the Abbott Prism assay. Positive samples were confirmed by appropriate methods. Of 222 samples, nine (4.1%) were reactive for all markers. After confirmation, seven samples were positive (i.e., 3.2% false-negative results) : five (2.3%) for the surface antigen of hepatitis B (HBsAg) and two (0.9%) for the antibody directed against the hepatitis C virus (HCV-Ab). No false negative results were observed for HIV-Ab (antibody directed against the Human Immunodeficiency Virus). The performance of the rapid tests used in Niamey to screen for transfusion-transmissible infections is not satisfactory, especially for hepatitis B and C. The use of more sensitive tests should be considered to minimize the risk of contaminating patients receiving blood components. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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