Epidemiological and clinical characteristics of 671 COVID-19 patients in Henan Province, China
| Autor: | Yifei Nie, Wanshen Guo, Yan Ma, Xueyong Huang, Xiao-Jing Shen, Xiaofeng Dai, Xiao-yan Tang, Xiaobai Zhang, Jitian Li, Haifeng Wang, Muge Qi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male China medicine.medical_specialty Pediatrics Adolescent Fever Coronavirus disease 2019 (COVID-19) Epidemiology Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Pneumonia Viral 030204 cardiovascular system & hematology Municipal level Betacoronavirus 03 medical and health sciences 0302 clinical medicine medicine Humans Henan province 030212 general & internal medicine Lung Pandemics Aged SARS-CoV-2 business.industry Transmission (medicine) Mortality rate COVID-19 General Medicine Middle Aged Coronavirus Cough Radiological weapon Hypertension Female Radiography Thoracic Original Article Coronavirus Infections Tomography X-Ray Computed business |
| Zdroj: | International Journal of Epidemiology |
| ISSN: | 1464-3685 0300-5771 |
| DOI: | 10.1093/ije/dyaa081 |
| Popis: | Background Despite many reports on the characteristics of coronavirus disease 2019 (COVID-19) in Wuhan, China, relatively little is known about the transmission features of COVID-19 outside Wuhan, especially at the provincial level. Methods We collected epidemiological, demographic, clinical, laboratory, radiological and occupation information, along with contact history, of 671 patients with laboratory-confirmed COVID-19 reported from January 23 to February 5, 2020, in Henan province, China. We described characteristics of these cases, compared the diagnostic accuracy and features of blood testing, computed tomography (CT) scans and X-rays, and analysed SARS-CoV-2 transmission sources and patients’ occupations in Henan province. Results The mean age of patients in this case series was 43 years, 56.2% were male and 22.4% had coexisting medical disorders. The death rate was 0.3%. Fourteen patients did not show any symptoms. Lymphocyte percentage was associated with disease severity (χ2 = 6.71, P = 0.035) but had a large variation in each sample group. The mean time from illness onset to diagnosis was 5.6 days. A total of 330 patients had ever lived in or visited Wuhan, 150 had contact with confirmed cases, 323 had been to a hospital and 119 had been to a wet market. There were 33 patients who did not have a traceable transmission source, with 21.2% of these being farmers and 15.2% being workmen. Conclusions Lymphocyte percentage was a sign of severe COVID-19 in general but was not a good diagnostic index. Longer time from illness onset to diagnosis was associated with higher COVID-19 severity, older age, higher likelihood of having coexisting cardiovascular diseases including hypertension, and being male. Farming was found to be a high-risk occupation in Henan province, China. |
| Databáze: | OpenAIRE |
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