Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma

Autor: Karen J. Marcus, Robert C. Shamberger, Harry P.W. Kozakewich, Christopher B. Weldon, Jordan R. Gutweiler, Heung Bae Kim, David C. Yu
Rok vydání: 2008
Předmět:
Hepatoblastoma
Male
Pathology
medicine.medical_specialty
Neoplasms
Radiation-Induced

medicine.medical_treatment
Adrenal Gland Neoplasms
Malignancy
Carboplatin
Antibodies
Monoclonal
Murine-Derived

Neuroblastoma
Antineoplastic Combined Chemotherapy Protocols
Granulocyte Colony-Stimulating Factor
Parenchyma
Biopsy
medicine
Hepatectomy
Humans
Ifosfamide
Cyclophosphamide
Melphalan
Bone Marrow Transplantation
Etoposide
Mesna
Incidental Findings
medicine.diagnostic_test
business.industry
Liver Neoplasms
Focal nodular hyperplasia
Antibodies
Monoclonal

Neoplasms
Second Primary

General Medicine
medicine.disease
Combined Modality Therapy
Radiation therapy
Focal Nodular Hyperplasia
Vincristine
Child
Preschool

Immunoglobulin G
Pediatrics
Perinatology and Child Health

Radiotherapy
Adjuvant

Surgery
Fluorouracil
Cisplatin
Tomography
X-Ray Computed

business
Zdroj: Journal of Pediatric Surgery. 43:2297-2300
ISSN: 0022-3468
DOI: 10.1016/j.jpedsurg.2008.08.069
Popis: Focal nodular hyperplasia (FNH) is a benign, poorly understood hepatic tumor that is rare in children. Although there is no evidence for malignant degeneration, FNH can occur adjacent to a malignancy. Here, the case of a 4-year-old boy with a hepatic mass and history of stage IV neuroblastoma is presented. Initial imaging and core-needle biopsy were consistent with FNH. However, after left lateral segmentectomy, pathologic examination revealed a malignant tumor most consistent with small cell undifferentiated hepatoblastoma as well as 3 foci of FNH in the surrounding parenchyma.
Databáze: OpenAIRE