Higher Serum Triglyceride Level in Patients with Acute Ischemic Stroke Is Associated with Lower Infarct Volume on CT Brain Scans

Autor: Vladimir Trkulja, Nedeljko Sokol, Dražen Milevčić, Ivan Pavliček, Slaven Pikija, Spomenka Kidemet-Piskač
Rok vydání: 2006
Předmět:
Zdroj: European Neurology. 55:89-92
ISSN: 1421-9913
0014-3022
DOI: 10.1159/000092780
Popis: We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47–93 years) with anterior circulation (75%), posterior circulation (9%) or lacunar infarcts (16%) were examined. All patients were admitted within 24 h of the symptom onset, and CT scans were taken over the subsequent 24–72 h. With adjustment for the infarct type, age, sex, timing of CT imaging (24–36, >36–48 or >48–72 h since admission), atrial fibrillation, hypertension, fasting cholesterol and glucose levels, a higher (≧1.70 mmol/l) fasting serum triglyceride level (within 24 h after admission) was associated with a lower infarct volume (p = 0.014). In line with a recent report on milder clinical symptoms in acute ischemic stroke patients with higher triglycerides, the results suggest an independent association between serum triglyceride level and stroke severity.
Databáze: OpenAIRE