The Gut Microbiome: Human Health and Inflammatory Skin Diseases
| Autor: | Emily A. Mann, Jean S. McGee, Hye Jin Chung, Edward Bae, Darya Kostyuchek |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Inflammation
Cell signaling business.industry Gastrointestinal Microbiome Human microbiome Dermatology Atopic dermatitis Disease Review Article medicine.disease 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Immune system 030220 oncology & carcinogenesis Psoriasis Immunology Rosacea Medicine Microbiome Erratum business Gastrointestinal microbiome |
| Zdroj: | Annals of Dermatology |
| ISSN: | 2005-3894 1013-9087 |
| Popis: | The human microbiome is a rich environment consisting of bacteria, fungi and other commensal microorganisms of the gut, mucosa and skin. The functional role of the gut microbiome includes facilitation in metabolism of macronutrients, maturation of the immune system, and production of pro- or anti-inflammatory signaling molecules and peptides. The identification of these resident organisms has brought about a new understanding of disease processes. Nevertheless, more questions remain regarding the interactions within the microbiome, its interactions with the host, and its contributions to the pathophysiology of disease. The purpose of this review is to examine the existing medical literature to highlight the role of the gut microbiome in human health, also paying attention to its role in several inflammatory skin diseases, namely atopic dermatitis, psoriasis, and rosacea. (Ann Dermatol 32(4) 265∼272, 2020) |
| Databáze: | OpenAIRE |
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