Expression and localization of follicle-stimulating hormone receptor in the yak uterus during different stages of the oestrous cycle
| Autor: | Ayimuguli Abudureyimu, Rongxin Zang, Ren Rui, Yong Cai, Zhongren Ma, Sheng-dong Huo, Yan Cui, Yang Jutian |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
endocrine system Pituitary gland Angiogenesis Uterus Gene Expression Estrous Cycle Biology Andrology 03 medical and health sciences Endocrinology Placenta medicine Animals Receptor Estrous cycle urogenital system 030104 developmental biology medicine.anatomical_structure Receptors FSH Animal Science and Zoology Cattle Female Follicle-stimulating hormone receptor Biotechnology Hormone |
| Zdroj: | Reproduction in domestic animals = Zuchthygiene. 53(6) |
| ISSN: | 1439-0531 |
| Popis: | Morphological changes of the uterus and alterations in its secretory activity under the influence of steroid hormones been well documented. The oestrous cycle is also associated with significant changes in plasma follicle-stimulating hormone (FSH), whose effects are mediated through its receptor (FSHR). Reports showed that in many mammals, FSHR was expressed in gonadal and extragonadal tissues including cervix, female reproductive tract, and pituitary gland. Follicle-stimulating hormone (FSH) signals through endothelial FSHR directly stimulate angiogenesis and involved in the timing of birth in human, and the presence of FSHR in the placenta is essential for normal pregnancy in mice. But little is known about FSHR expression in the yak uterus. The main objective of the present study was to determine the expression and localization of FSHR in the yak uterus during different phases of the oestrous cycle. Results showed that FSHR protein was localized in the surface and glandular epithelial cells, stroma cells, myometrial smooth muscle cells and blood vessel endothelial cells. The expression of FSHR protein peaked at oestrus, significantly decreased at dioestrus (p |
| Databáze: | OpenAIRE |
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