A comparison of intramuscular benzathine penicillin and oral sulfonamide in the control of rheumatic recurrences
| Autor: | Carolyn M. McCue, Count D. Gibson, Lillian C. Lindemann |
|---|---|
| Rok vydání: | 1955 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Antibiotics Penicillins Injections Intramuscular Sulfanilamide Sulfadiazine Blood serum Recurrence Sulfanilamides Benzathine penicillin g Humans Medicine Benzathine penicillin Sulfonamides business.industry Sulfonamide (medicine) medicine.disease Surgery Pediatrics Perinatology and Child Health Penicillin G Benzathine Rheumatic fever Rheumatic Fever business Intramuscular injection medicine.drug |
| Zdroj: | The Journal of Pediatrics. 47:450-460 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(55)80056-x |
| Popis: | Summary 1. One thousand, one hundred three intramuscular injections of 1,200,000 units of benzathine penicillin to fortysix patients with recent rheumatic fever were given for an average of twenty-four months without a single recurrence. Two patients with old failure and enlarged hearts continue to smoulder but are still living. 2. A similar group of forty-six patients on sulfonamides showed a recurrence rate of 4.3 per cent in an average period of 38.6 months. One child in this group died from what we believe to have been an intercurrent infection and three others had vague aches but no clear-cut recurrences. 3. When added to the previous studies, the evidence is increasingly strong for large-scale use of benzathine penicillin G intramuscularly for prevention of rheumatic recurrences. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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