A case of entecavir-associated bullous fixed drug eruption and a review of literature
| Autor: | Arzu Ataseven, İlkay Özer, Sıddıka Fındık, Selami Aykut Temiz |
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| Přispěvatelé: | Selami Aykut Temiz: 0000-0003-4878-0045, İlkay Özer: 0000-0001-6170-0930, Arzu Ataseven: 0000-0001-5372-0712, Sıddıka Fındık: 0000-0002-3364-7498, Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Anabilim Dalı, Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Anabilim Dalı |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
myalgia
Drug Hepatitis B virus medicine.medical_specialty Guanine Erythema media_common.quotation_subject Case Report Antiviral Agents 03 medical and health sciences Fixed drug eruption 0302 clinical medicine medicine Humans media_common business.industry Gastroenterology Entecavir Middle Aged Hepatitis B medicine.disease Dermatology Drug eruption Metronidazole 030220 oncology & carcinogenesis Bullous fixed drug eruption Female 030211 gastroenterology & hepatology Drug Eruptions Bullous drug reaction medicine.symptom business medicine.drug |
| Popis: | WOS:000462167400013 PubMed ID: 30459136 Fixed drug eruption (FDE) is a type of drug reaction characterized by localized erythema, hyperpigmentation, and bullous at the samesite(s), generally observed following every intake of a causative drug. Delayed-type cellular hypersensitivity (Type IVC) is considered toplay a role in FDE etiology. Several antibiotics, barbiturates, oral contraceptives, nonsteroidal anti-inflammatory drugs, laxative-containing phenolphthalein, metronidazole, and quinine are known to be the primary drugs responsible for FDE. Bullous FDE, on the otherhand, is a relatively rare form of FDE. Hepatitis B is a significant worldwide health problem, and entecavir is a common nucleoside(deoxyguanosine) analog used for treating hepatitis B; however, it has various side effects, such as lactic acidosis, myalgia, azotemia,hypophosphatemia, headache, diarrhea, pancreatitis, and neuropathy, and, in rare cases, cutaneous drug eruption. Our aim is to presenta case of entecavir-associated bullous drug reaction, which has not been reported in the literature. Furthermore, we performed a reviewof literature to compile previously reported entecavir-associated drug reactions. |
| Databáze: | OpenAIRE |
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