Osteosarcoma of the spine: surgical treatment and outcomes
| Autor: | Xinghai Yang, Zhipeng Wu, Quan Huang, Junming Ma, Wei Zheng, Yong Teng, Huazi Xu, Zhiming Cui, Jianru Xiao, Dapeng Feng, Wending Huang, Tielong Liu |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Total en bloc spondylectomy medicine.medical_specialty Adolescent Total piecemeal spondylectomy Young Adult Surgical oncology medicine Humans Young adult Surgical treatment Neoplasm Staging Retrospective Studies Osteosarcoma Retrospective review Spinal Neoplasms business.industry Research Thoracolumbar spine Retrospective cohort study Middle Aged Prognosis medicine.disease Spine Surgery Oncology Vertebrectomy Female Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | World Journal of Surgical Oncology |
| ISSN: | 1477-7819 |
| Popis: | BackgroundThe goal of this study was to determine whether there are correlations between various options of surgical treatment and long-term outcome for spinal osteosarcoma.MethodsThis was a retrospective review of 16 patients with spinal osteosarcoma, who underwent surgical treatment from 1999 to 2010. Seven patients were given totalen blocspondylectomy (TES), while nine received piecemeal resection (there were seven cases of total piecemeal spondylectomy, one of sagittal resection, and one of vertebrectomy). The outcome and prognosis of the patients were evaluated, grouped by surgical treatment.ResultsAll 16 cases were followed for an average of 42.4 months. At follow-up, all patients noted that pain had eased or had gradually disappeared. Three months after surgery, eight patients (50.0%) had improved 1 to 2 grades in their neurological status, based on Frankel scoring. Six (37.5%) patients experienced local recurrence of the tumor, nine (56.3%) had metastases, and five (31.3%) died of the disease. Of the six patients who received a wide or marginalen blocresection, none developed local recurrence or died from the disease. Conversely, of the ten patients who received intralesional or contaminated resections, six (60%) relapsed and five (50%) died from the disease.ConclusionsTES, with a wide margin, should be planned for patients with osteosarcoma of the cervical and thoracolumbar spine, whenever possible. When the patients are not candidates foren blocresection, total piecemeal spondylectomy is an appropriate choice for osteosarcoma in the mobile spine. |
| Databáze: | OpenAIRE |
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