Estimation of the Initial Dose Setting of Vancomycin Therapy With Use of Cystatin C as a New Marker of Renal Function
| Autor: | Akihiro Tanaka, Mitsuharu Murase, Tomoyoshi Inoue, Masaki Yasukawa, Ikuya Sakai, Katsuya Suemaru, Hiroaki Araki, Tatsuya Nishimiya, Hitoshi Hasegawa, Takashi Otsuka, Keiko Ido |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Initial dose Urology Renal function Kidney Function Tests urologic and male genital diseases Sensitivity and Specificity chemistry.chemical_compound Vancomycin Internal medicine Elderly population medicine Humans Pharmacology (medical) Cystatin C Aged Antibacterial agent Aged 80 and over Pharmacology Creatinine biology medicine.diagnostic_test business.industry Middle Aged Staphylococcal Infections Cystatins Anti-Bacterial Agents Endocrinology chemistry Therapeutic drug monitoring biology.protein Female Methicillin Resistance Drug Monitoring business Biomarkers medicine.drug |
| Zdroj: | Therapeutic Drug Monitoring. 29:261-264 |
| ISSN: | 0163-4356 |
| DOI: | 10.1097/ftd.0b013e31803bcfd2 |
| Popis: | In recent years, it has been suggested that the glomerular filtration rate (GFR) can be predicted on the basis of serum cystatin C concentrations and that this measurement is more sensitive than serum creatinine concentration as a marker of renal function. In this study, to investigate the clinical utility of the initial dose setting of vancomycin by the population mean method with use of serum cystatin C as a marker of renal function, we compared the correlations between measured vancomycin concentrations and predicted vancomycin concentrations based on serum cystatin C or serum creatinine concentrations in elderly (>/=65 years old) and nonelderly ( |
| Databáze: | OpenAIRE |
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