Added value of strain elastography in the characterisation of breast lesions: A prospective study
| Autor: | Dimpi Sinha, Sukrity Sharma, Sudhir Kale, Nischal G Kundaragi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Strain elastography Radiological and Ultrasound Technology business.industry 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Added value Medicine Radiology Nuclear Medicine and imaging Radiology Prospective cohort study business Original Research |
| Zdroj: | Ultrasound |
| ISSN: | 1743-1344 1742-271X |
| DOI: | 10.1177/1742271x20912762 |
| Popis: | Background Elastography is a new promising ultrasonographic technique which is used to differentiate benign and malignant breast lesions based on the stiffness of the lesion. Purpose To determine the role of strain elastography in characterisation of breast lesions and to compare the diagnostic performances of strain elastography and conventional ultrasound (US). Methods In total, 113 breast lesions in 100 women were prospectively evaluated by US and strain elastography followed by the histopathological examination. Elastography score based on the Tsukuba colour scale and strain ratio were determined for each lesion. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value were calculated for each modality and the diagnostic performances were compared. The best cut-off point was calculated for each of the elastography parameters using the receiver operator curve analysis. Results Out of the 113 lesions, 40 were malignant (35.4%) and 73 were benign (64.6%). The area under the curve for elastography score showed significant difference with that of US: 0.98 versus 0.90 (Difference = 0.08, p =0.02). The elastography parameters were more specific as compared to US (ES-95 and SR-93% vs. 63%, p Conclusion Strain elastography is a useful adjunct to conventional ultrasonography. The combined use of strain elastography and ultrasound improves the characterisation of breast lesions and helps in down-staging of assigned BI-RADS category, thereby avoiding unnecessary biopsies. ES is the most useful elastography parameter to differentiate between benign and malignant breast lesions. |
| Databáze: | OpenAIRE |
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