Mitragynine 'Kratom' related fatality: a case report with postmortem concentrations
| Autor: | Susan Stolberg, Amber Trochta, Steven C. Campman, Iain M. McIntyre |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Health Toxicology and Mutagenesis Mitragyna speciosa Mirtazapine Venlafaxine Urine Pharmacology Toxicology Gas Chromatography-Mass Spectrometry Analytical Chemistry chemistry.chemical_compound Forensic Toxicology Fatal Outcome medicine Environmental Chemistry Humans Chemical Health and Safety biology business.industry Diphenhydramine Pulmonary edema medicine.disease biology.organism_classification Secologanin Tryptamine Alkaloids chemistry Mitragynine Toxicity business medicine.drug |
| Zdroj: | Journal of analytical toxicology. 39(2) |
| ISSN: | 1945-2403 |
| Popis: | A 24-year-old man whose medical history was significant for alcohol abuse and depression was found unresponsive in bed. He had several prior suicide attempts with ‘pills’ and had also been hospitalized for an accidental overdose on a previous occasion. Autopsy findings were unremarkable apart from pulmonary edema and congestion, and urinary retention. Postmortem peripheral blood initially screened positive for mitragynine ‘Kratom’ (by routine alkaline drug screen by gas chromatography –mass spectrometry, GC–MS), which was subsequently confirmed by a specific GC–MS selective ion mode analysis following solid-phase extraction. Concentrations were determined in the peripheral blood (0.23 mg/L), central blood (0.19 mg/L), liver (0.43 mg/kg), vitreous ( |
| Databáze: | OpenAIRE |
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