Relationships among purine nucleoside metabolism, adenosine triphosphate catabolism, and glycolysis in human erythrocytes
Autor: | Smith Cm, Henderson Jf, George Zombor, Burridge Pw, Barankiewicz G |
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Rok vydání: | 1979 |
Předmět: |
Purine
Erythrocytes Catabolism Adenylate kinase Iodoacetates General Medicine Metabolism Purine Nucleosides Deoxyglucose Molecular biology Tubercidin chemistry.chemical_compound Adenosine Triphosphate chemistry Biochemistry parasitic diseases Adenosine Deaminase Inhibitors Lactates Humans Sodium Fluoride Glycolysis Adenosine Deaminase Inhibitor Adenosine triphosphate |
Zdroj: | Canadian journal of biochemistry. 57(6) |
ISSN: | 0008-4018 |
Popis: | In human erythrocytes incubated with both naturally occurring purine nucleosides and with a variety of purine nucleoside analogs, ATP catabolism was accelerated and lactate accumulation was increased. Tubercidin was a particularly potent inducer of ATP catabolism. In cells incubated with tubercidin, the major route of adenylate metabolism was deamination, whereas in cells incubated with deoxyglucose, the major pathway was dephosphorylation. |
Databáze: | OpenAIRE |
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