Contrast‐Enhanced Ultrasound for Differentiation Between Poorly Differentiated Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Autor: Wei Wang, Xiaoyan Xie, Li-Da Chen, Xin Zheng, Huanling Guo, Mei-Qing Cheng, Meng-Fei Xian, Dan Zeng, Hui Huang, Ming Kuang, Ming-De Lu
Rok vydání: 2021
Předmět:
Zdroj: Journal of Ultrasound in Medicine. 41:1213-1225
ISSN: 1550-9613
0278-4297
DOI: 10.1002/jum.15812
Popis: PURPOSE To evaluate the diagnostic performance of LR-5 for diagnosing poorly differentiated hepatocellular carcinoma (p-HCC). To build a contrast-enhanced ultrasound (CEUS) signature for improving the differential diagnostic performance between p-HCC and intrahepatic cholangiocarcinoma (ICC). METHODS The B-mode ultrasound (BUS) and CEUS features of 60 p-HCCs and 56 ICCs were retrospectively analyzed. The CEUS LI-RADS category was assigned according to CEUS LI-RADS v2017. A diagnostic CEUS signature was built based on the independent significant features. An ultrasound (US) signature combining both BUS and CEUS features was also built. The diagnostic performances of the CEUS signature, US signature, and LR-5 were evaluated by receiver operating characteristic (ROC) analysis. RESULTS One (1.7%) p-HCC and 26 (46.4%) ICC patients presented cholangiectasis or cholangiolithiasis (P
Databáze: OpenAIRE