Contrast‐Enhanced Ultrasound for Differentiation Between Poorly Differentiated Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
Autor: | Wei Wang, Xiaoyan Xie, Li-Da Chen, Xin Zheng, Huanling Guo, Mei-Qing Cheng, Meng-Fei Xian, Dan Zeng, Hui Huang, Ming Kuang, Ming-De Lu |
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Rok vydání: | 2021 |
Předmět: |
Carcinoma
Hepatocellular Radiological and Ultrasound Technology Receiver operating characteristic business.industry Liver Neoplasms Ultrasound Contrast Media Magnetic Resonance Imaging Sensitivity and Specificity Cholangiocarcinoma Bile Ducts Intrahepatic Bile Duct Neoplasms Poorly Differentiated Hepatocellular Carcinoma Humans Medicine Radiology Nuclear Medicine and imaging business Nuclear medicine Intrahepatic Cholangiocarcinoma Retrospective Studies Contrast-enhanced ultrasound |
Zdroj: | Journal of Ultrasound in Medicine. 41:1213-1225 |
ISSN: | 1550-9613 0278-4297 |
DOI: | 10.1002/jum.15812 |
Popis: | PURPOSE To evaluate the diagnostic performance of LR-5 for diagnosing poorly differentiated hepatocellular carcinoma (p-HCC). To build a contrast-enhanced ultrasound (CEUS) signature for improving the differential diagnostic performance between p-HCC and intrahepatic cholangiocarcinoma (ICC). METHODS The B-mode ultrasound (BUS) and CEUS features of 60 p-HCCs and 56 ICCs were retrospectively analyzed. The CEUS LI-RADS category was assigned according to CEUS LI-RADS v2017. A diagnostic CEUS signature was built based on the independent significant features. An ultrasound (US) signature combining both BUS and CEUS features was also built. The diagnostic performances of the CEUS signature, US signature, and LR-5 were evaluated by receiver operating characteristic (ROC) analysis. RESULTS One (1.7%) p-HCC and 26 (46.4%) ICC patients presented cholangiectasis or cholangiolithiasis (P |
Databáze: | OpenAIRE |
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