Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: A 3-year follow-up of the LADIS study cohort
| Autor: | C, Ryberg, E, Rostrup, O B, Paulson, F, Barkhof, P, Scheltens, E C W, van Straaten, W M, van der Flier, F, Fazekas, R, Schmidt, J M, Ferro, H, Baezner, T, Erkinjuntti, H, Jokinen, L-O, Wahlund, A, Poggesi, L, Pantoni, D, Inzitari, G, Waldemar, Kjell, Asplund |
|---|---|
| Přispěvatelé: | Radiology and nuclear medicine, Neurology, NCA - Neurodegeneration |
| Rok vydání: | 2011 |
| Předmět: |
Male
Aging medicine.medical_specialty Walking Corpus callosum Corpus Callosum Developmental psychology Cohort Studies White matter 03 medical and health sciences 0302 clinical medicine Atrophy Internal medicine medicine Humans Dementia Effects of sleep deprivation on cognitive performance 10. No inequality Aged 030304 developmental biology Memory Disorders 0303 health sciences Cognitive disorder Leukoaraiosis medicine.disease Hyperintensity medicine.anatomical_structure Neurology Cardiology Female Neurology (clinical) Psychomotor Disorders Cognition Disorders Psychology 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Ryberg, C, Rostrup, E, Paulson, O B, Barkhof, F, Scheltens, P, van Straaten, E C W, van der Flier, W M, Fazekas, F, Schmidt, R, Ferro, J M, Baezner, H, Erkinjuntti, T, Jokinen, H, Wahlund, L O, Poggesi, A, Pantoni, L, Inzitari, D & Waldemar, G 2011, ' Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: A 3-year follow-up of the LADIS study cohort ', Journal of the Neurological Sciences, vol. 307, no. 1-2, pp. 100-105 . https://doi.org/10.1016/j.jns.2011.05.002 Journal of the Neurological Sciences, 307(1-2), 100-105. Elsevier |
| ISSN: | 0022-510X |
| Popis: | The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive performance (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect