Comparison of Thyroid Imaging Reporting and Data Systems in Malignancy Risk Stratification of Indeterminate Thyroid Nodules
| Autor: | Kim, Bo Hyun |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Thyroid nodules
medicine.medical_specialty Endocrinology Diabetes and Metabolism Malignancy Risk Assessment Diseases of the endocrine glands. Clinical endocrinology Thyroid guidelines Endocrinology Republic of Korea medicine Data Systems Humans Thyroid Neoplasms Thyroid Nodule Thyroid imaging reporting and data systems Thyroid ultrasound Retrospective Studies Ultrasonography Thyroid business.industry medicine.disease RC648-665 United States Editorial medicine.anatomical_structure Risk stratification Original Article Radiology Indeterminate business |
| Zdroj: | Endocrinology and Metabolism, Vol 36, Iss 5, Pp 974-976 (2021) Endocrinology and Metabolism |
| ISSN: | 2093-5978 |
| Popis: | Background The management of cytologically indeterminate thyroid nodules is challenging for clinicians. This study aimed to compare the diagnostic performance of the Korean Thyroid Imaging Reporting and Data Systems (K-TIRADS) with that of the American College of Radiology (ACR)-TIRADS for predicting the malignancy risk of indeterminate thyroid nodules. Methods Thyroid nodules diagnosed by fine-needle aspiration (FNA) followed by surgery or core needle biopsy at a single referral hospital were enrolled. Results Among 200 thyroid nodules, 78 (39.0%) nodules were classified as indeterminate by FNA (Bethesda category III, IV, and V), and 114 (57.0%) nodules were finally diagnosed as malignancy by surgery or core needle biopsy. The area under the curve (AUC) was higher for FNA than for either TIRADS system in all nodules, while all three methods showed similar AUCs for indeterminate nodules. However, for Bethesda category III nodules, applying K-TIRADS 5 significantly increased the risk of malignancy compared to a cytological examination alone (50.0% vs. 26.5%, P=0.028), whereas applying ACR-TIRADS did not lead to a change. Conclusion K-TIRADS and ACR-TIRADS showed similar diagnostic performance in assessing indeterminate thyroid nodules, and K-TIRADS had beneficial effects for malignancy prediction in Bethesda category III nodules. |
| Databáze: | OpenAIRE |
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