Abdominal Adipose Tissue distribution on MRI and Diabetes
| Autor: | Michalis Mantatzis, Simoni A. Katergari, Thanos Milousis, Panos Prassopoulos, Dimitrios N. Papachristou, Andreas Delistamatis |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Wilcoxon signed-rank test Abdominal Fat Adipose tissue Sensitivity and Specificity Imaging Three-Dimensional Diabetes mellitus Image Interpretation Computer-Assisted Humans Medicine Distribution (pharmacology) Tissue Distribution Radiology Nuclear Medicine and imaging Adiposity Aged medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging Middle Aged Anthropometry medicine.disease Magnetic Resonance Imaging Adipose Tissue Diabetes Mellitus Type 2 Metabolic syndrome business Nuclear medicine Body mass index |
| Zdroj: | Academic Radiology. 21:667-674 |
| ISSN: | 1076-6332 |
| Popis: | To introduce a simple magnetic resonance imaging (MRI) protocol for quantitative assessment of intraperitoneal, retroperitoneal, and subcutaneous adipose tissue (AT) and to compare AT distribution between diabetic and nondiabetic individuals.Thirty-eight consecutive male diabetic patients (group A) and 38 males (who matched for body mass index [BMI]) without metabolic syndrome (group B) underwent abdominal MRI with a three-dimensional spoiled gradient echo T1-weighted sequence. The amounts of intraperitoneal, retroperitoneal, and subcutaneous AT were calculated on a workstation, after manual anatomic segmentation and were correlated with 10 anthropometric measurements. Pearson product-moment correlation coefficients were used for correlation of AT volumes with anthropometric measurements, Wilcoxon test to compare AT measurements between automatic and manual technique used, and unpaired t test to compare volumes of AT compartments between group A and B.Diabetic patients exhibited larger amount of intraperitoneal and retroperitoneal AT than normal individuals at all levels (t = 2.02,P.05). Among anthropometric measurements, the waist circumference, BMI, and body fat percentage exhibited the best correlations with intraperitoneal and retroperitoneal AT (group A (r) = 0.88/0.78/0.0.69 and group B (r) = 0.91/0.87/0.81). The L2-L5 set of images was found to be the most representative of the amount of AT volumes.Amount and distribution of AT can be accurately and easily assessed on MRI. Quantification of intraabdominal AT may promote the role of imaging in the study of metabolic syndrome. |
| Databáze: | OpenAIRE |
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