Neuromuscular Control before and after Independent Walking Onset in Children with Cerebral Palsy
| Autor: | Coen S. Zandvoort, Laura A. van de Pol, R. Jeroen Vermeulen, Annike Bekius, Nadia Dominici, Jaap Harlaar, Jennifer N. Kerkman, A.I. Buizer, Andreas Daffertshofer |
|---|---|
| Přispěvatelé: | Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Pediatric surgery, Rehabilitation medicine, AMS - Rehabilitation & Development, Coordination Dynamics, Knowledge, Information and Innovation, Amsterdam Movement Sciences, IBBA |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
030506 rehabilitation
electromyography Electromyography Walking lcsh:Chemical technology Biochemistry Analytical Chemistry Leg muscle 0302 clinical medicine Medicine motor development lcsh:TP1-1185 Muscle synergy Child Instrumentation Gait Motor skill medicine.diagnostic_test TYPICALLY DEVELOPING-CHILDREN Skeletal Atomic and Molecular Physics and Optics Biomechanical Phenomena CP Child Preschool Muscle Neuromuscular control 0305 other medical science REPEATABILITY INTERVENTION medicine.medical_specialty SYNERGIES MOTOR CONTROL gait Article CLASSIFICATION Cerebral palsy Independent walking 03 medical and health sciences Physical medicine and rehabilitation muscle synergies Humans Electrical and Electronic Engineering Preschool Muscle Skeletal early brain lesions COMPLEXITY Cerebral Palsy/diagnosis business.industry Cerebral Palsy Infant MUSCLE ACTIVATION PATTERNS medicine.disease HIGH-RISK business human activities 030217 neurology & neurosurgery |
| Zdroj: | Sensors, 21(8):2714. MDPI AG Bekius, A, Zandvoort, C S, Kerkman, J N, van de Pol, L A, Vermeulen, R J, Harlaar, J, Daffertshofer, A, Buizer, A I & Dominici, N 2021, ' Neuromuscular Control before and after Independent Walking Onset in Children with Cerebral Palsy ', Sensors (Basel, Switzerland), vol. 21, no. 8, 2714 . https://doi.org/10.3390/s21082714 Sensors (Basel, Switzerland) Sensors, 21(8):2714. Multidisciplinary Digital Publishing Institute (MDPI) Sensors, 21(8) Sensors Volume 21 Issue 8 Bekius, A, Zandvoort, C S, Kerkman, J N, van de Pol, L A, Jeroen Vermeulen, R, Harlaar, J, Daffertshofer, A, Buizer, A I & Dominici, N 2021, ' Neuromuscular control before and after independent walking onset in children with cerebral palsy ', Sensors, vol. 21, no. 8, 2714 . https://doi.org/10.3390/s21082714 Sensors (Basel, Switzerland), 21(8):2714. Multidisciplinary Digital Publishing Institute (MDPI) Sensors, Vol 21, Iss 2714, p 2714 (2021) |
| ISSN: | 1424-8220 |
| DOI: | 10.3390/s21082714 |
| Popis: | Early brain lesions which produce cerebral palsy (CP) may affect the development of walking. It is unclear whether or how neuromuscular control, as evaluated by muscle synergy analysis, differs in young children with CP compared to typically developing (TD) children with the same walking ability, before and after the onset of independent walking. Here we grouped twenty children with (high risk of) CP and twenty TD children (age 6.5–52.4 months) based on their walking ability, supported or independent walking. Muscle synergies were extracted from electromyography data of bilateral leg muscles using non-negative matrix factorization. Number, synergies’ structure and variability accounted for when extracting one (VAF1 ) or two (VAF2 ) synergies were compared between CP and TD. Children in the CP group recruited fewer synergies with higher VAF1 and VAF2 compared to TD children in the supported and independent walking group. The most affected side in children with asymmetric CP walking independently recruited fewer synergies with higher VAF1 compared to the least affected side. Our findings suggest that early brain lesions result in early alterations of neuromuscular control, specific for the most affected side in asymmetric CP. |
| Databáze: | OpenAIRE |
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