Early Clinical Applications of Lung Scintiscanning
| Autor: | Joseph E. Whitley, Robert W. Prichard, James L. Quinn, Allen S. Hudspeth |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
Lung Diseases
Radioisotopes Pathology medicine.medical_specialty Lung Neoplasms Lung business.industry Pulmonary disease Spleen Human serum albumin Pulmonary scans medicine.anatomical_structure Geriatrics Iodine Isotopes Neoplasms Pulmonary arterial tree Medicine Abdomen Radiography Thoracic Radiology Nuclear Medicine and imaging Radionuclide Imaging business Nuclear medicine Thoracic Radiography medicine.drug |
| Zdroj: | Radiology. 82:315-317 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/82.2.315 |
| Popis: | Scintiscanning of the lungs offers a new approach to the diagnosis of pulmonary disease. Denatured iodinated human serum albumin particles, 10 to 50 microns in diameter, are obtained by adjusting the pH, time, and temperature of incubation (1, 2). Following their intravenous injection, these particles are temporarily delayed in the pulmonary arterial tree (3–5). After one hour, radioactivity increases in the liver and spleen and diminishes over the lung, supporting the thesis that the particles are broken down to smaller aggregates which then localize in the liver and spleen. At twenty-four hours there is little radioactivity over the lungs or abdomen. The technic was found to be useful in outlining experimentally produced pulmonary infarcts in dogs (4, 5). This report contains our initial clinical experience in man. Ten pulmonary scans were performed on 9 patients with various diagnoses. The results are presented in Table I. There were no untoward reactions and the patients noted no unusual feeling attri... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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