Need for Ethnic and Population Diversity in Psychosis Research
| Autor: | Ran Barzilay, Carla Burkhard, Rajiv Radhakrishnan, Sinan Guloksuz, Saba Cicek |
|---|---|
| Přispěvatelé: | Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Exposome
Biomedical Research AcademicSubjects/MED00810 Research Subjects DISORDERS BIRTH media_common.quotation_subject Population Ethnic group population SEASON Criminology exposome diversity 03 medical and health sciences Race (biology) 0302 clinical medicine Empirical research Population Groups Humans genetics education race METAANALYSIS media_common health disparities RISK education.field_of_study Environment and Schizophrenia—Feature Editor: Jim van Os Health equity 030227 psychiatry schizophrenia Psychiatry and Mental health Psychotic Disorders IMMIGRATION ethnicity Psychology environment GENOMICS 030217 neurology & neurosurgery Social structure Diversity (politics) |
| Zdroj: | Schizophrenia Bulletin, 47(4), 889-895. Oxford University Press Schizophrenia Bulletin |
| ISSN: | 1745-1701 0586-7614 |
| DOI: | 10.1093/schbul/sbab048 |
| Popis: | This article aims to evaluate “racial”, ethnic, and population diversity—or lack thereof—in psychosis research, with a particular focus on socio-environmental studies. Samples of psychosis research remain heavily biased toward Western, Educated, Industrialized, Rich, and Democratic (WEIRD) societies. Furthermore, we often fail to acknowledge the lack of diversity, thereby implying that our findings can be generalized to all populations regardless of their social, ethnic, and cultural background. This has major consequences. Clinical trials generate findings that are not generalizable across ethnicity. The genomic-based prediction models are far from being applicable to the “Majority World.” Socio-environmental theories of psychosis are solely based on findings of the empirical studies conducted in WEIRD populations. If and how these socio-environmental factors affect individuals in entirely different geographic locations, gene pools, social structures and norms, cultures, and potentially protective counter-factors remain unclear. How socio-environmental factors are assessed and studied is another major shortcoming. By embracing the complexity of environment, the exposome paradigm may facilitate the evaluation of interdependent exposures, which could explain how variations in socio-environmental factors across different social and geographical settings could contribute to divergent paths to psychosis. Testing these divergent paths to psychosis will however require increasing the diversity of study populations that could be achieved by establishing true partnerships between WEIRD societies and the Majority World with the support of funding agencies aspired to foster replicable research across diverse populations. The time has come to make diversity in psychosis research more than a buzzword. |
| Databáze: | OpenAIRE |
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