Binding studies of cucurbit[7]uril with gold nanoparticles bearing different surface functionalities

Autor:	Krishnendu Saha, Gulen Yesilbag Tonga, Ziwen Jiang, Riddha Das, Singyuk Hou, Tsukasa Mizuhara, Vincent M. Rotello
Rok vydání:	2015
Předmět:	Stereochemistry Organic Chemistry Supramolecular chemistry Isothermal titration calorimetry Ring (chemistry) Biochemistry Binding constant Article Para position chemistry.chemical_compound Benzylamine chemistry Colloidal gold Drug Discovery Polymer chemistry Benzene
Zdroj:	Tetrahedron Letters. 56:3653-3657
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2015.04.125
Popis:	Host–guest interactions between a synthetic receptor, cucurbit[7]uril (CB[7]), and gold nanoparticles (AuNPs) have been quantified using isothermal titration calorimetry. AuNPs were functionalized with ligands containing tertiary or quaternary benzylamine derivatives, with electron donating or withdrawing groups at the para position of the benzene ring. Analysis of binding interactions reveals that functional groups at the para position have no significant effect on binding constant. However, headgroups bearing a permanent positive charge increased the binding of AuNPs to CB[7] ten-fold compared to monomethyl counterparts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff4e210347874156d9bd8a39b8b1987 https://doi.org/10.1016/j.tetlet.2015.04.125 Zobrazit plný text záznamu Full Text from ScienceDirect