Chronic Q fever: An ongoing challenge in diagnosis and management
| Autor: | Nicola Guest, Peter Hewins, Ira Das, Richard P. Steeds |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Pediatrics medicine.medical_specialty Pathology biology Article Subject business.industry Q fever Infectious and parasitic diseases RC109-216 medicine.disease Coxiella burnetii biology.organism_classification Microbiology QR1-502 Duke criteria Serology Generally unwell Infectious Diseases Aortic valve replacement Chronic Q fever medicine Endocarditis business |
| Zdroj: | Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 25, Iss 1, Pp 35-37 (2014) |
| ISSN: | 1712-9532 |
| DOI: | 10.1155/2014/863678 |
| Popis: | Chronic Q fever is a potentially fatal disease. The current difficulty in the diagnosis of this condition is discussed in the present article. A 51-year-old woman with a history of aortic valve replacement presented with complaints of feeling generally unwell, pyrexia and occasional unproductive cough over a period of several weeks. Phase 1 immunoglobulin G titre toCoxiella burnetiiwas initially detected at a low level (1:320, detected using immunofluorescence) and was not considered to be significant according to the modified Duke criteria. Later in the course of her illness, the patient’s antibody titre rose to a high level (1:1280). The issues regarding current laboratory diagnosis and management of Q fever are discussed. Chronic Q fever can be associated with an inadequate serological response. Close follow-up of cases is essential. The recommended serological criteria for the diagnosis of Q fever endocarditis needs to be revisited. |
| Databáze: | OpenAIRE |
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