Recording the wild lives of immune cells
| Autor: | Sean P. Arlauckas, Ralph Weissleder, Mikael J. Pittet, Christopher Garris |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Study drug Innate immune system Intravital Microscopy Immunology Cell Immunity General Medicine Biology Immune System/cytology Adaptive Immunity Article Immunity Innate 03 medical and health sciences 030104 developmental biology medicine.anatomical_structure Immune system Immune System Microscopic imaging medicine Innate Animals Effector functions Neuroscience |
| Zdroj: | Science Immunology, Vol. 3, No 27 (2018) P. eaaq0491 |
| ISSN: | 2470-9468 |
| Popis: | Intravital microscopic imaging can uncover fundamental aspects of immune cell behavior in real time in both healthy and pathological states. Here, we discuss approaches for single-cell imaging of adaptive and innate immune cells to explore how they migrate, communicate, and mediate regulatory or effector functions in various tissues throughout the body. We further review how intravital single-cell imaging can be used to study drug effects on immune cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|