Primary immunodeficiency from B-cell defect: a case series of 6 patients seen in a national tertiary hospital in the Philippines
| Autor: | Carol Stephanie C. Tan-Lim, Mary Anne R. Castor |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty biology business.industry Case Report Dermatology medicine.disease Sepsis 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030228 respiratory system Agammaglobulinemia B-lymphocytes medicine Primary immunodeficiency biology.protein Immunology and Allergy General hospital Antibody business Immune deficiency syndromes Rest (music) B cell |
| Zdroj: | Asia Pacific Allergy |
| ISSN: | 2233-8276 |
| DOI: | 10.5415/apallergy.2021.11.e7 |
| Popis: | Primary immunodeficiency disorders, although rare, pose a significant burden in the quality of life of afflicted patients and their families. The most common of these disorders are caused by B-cell defects. A total of 6 patients were seen and diagnosed in a national tertiary hospital in the Philippines from 1996 to 2018. These patients were admitted due to various infections, and were subsequently diagnosed to have B-cell defects. Four out of the 6 patients have genetic studies confirming the diagnosis of X-linked agammaglobulinemia. One patient succumbed to sepsis at 10 years of age, while the rest are on follow-up at the Philippine General Hospital for intravenous immunoglobulin infusion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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