Clinical Significance of Implantation Metastases After Surgical Treatment of Cholangiocarcinoma

Autor: M. N. Van Der Heyde, P. C. M. Verbeek, A. Bosma, T. Ramsoekh
Rok vydání: 1990
Předmět:
Zdroj: Seminars in Liver Disease. 10:142-144
ISSN: 1098-8971
0272-8087
DOI: 10.1055/s-2008-1040467
Popis: Cytologic examination of bile obtained during surgery from intrahepatic bile ducts in patients with malignant proximal bile duct obstruction has shown a high incidence of tumor cells. Spill of bile occurs frequently during these operations and postoperative bile leakage often occurs. Typical implantation metastases were detected in three patients who underwent resective surgery for bile duct cancer. In addition, peritoneal spread of bile duct carcinoma was found on postmortem examination in seven of ten patients who died 6 to 27 months after resection of the hilar tumor. A relation between tumor-positive bile cytologic findings, tumor spill, and seeding during surgery is likely to exist. It is recommended that during surgery the utmost care should be taken to prevent spill of bile.
Databáze: OpenAIRE