Non-homologous end joining: Emerging themes and unanswered questions
| Autor: | Sarvan Kumar Radhakrishnan, Susan P. Lees-Miller, Nicholas Jette |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
DNA End-Joining Repair
Ku80 DNA repair DNA-Activated Protein Kinase Computational biology Biology Biochemistry Article Homology directed repair Humans DNA Breaks Double-Stranded Molecular Biology Replication protein A Genetics Cell Cycle fungi Nuclear Proteins Cell Biology DNA repair protein XRCC4 3. Good health Non-homologous end joining enzymes and coenzymes (carbohydrates) DNA Repair Enzymes embryonic structures Nucleotide excision repair |
| Zdroj: | DNA Repair. 17:2-8 |
| ISSN: | 1568-7864 |
| Popis: | Non-homologous end joining (NHEJ) is the major pathway for the repair of ionizing radiation induced DNA double strand breaks in human cells. Here, we discuss current insights into the mechanism of NHEJ and the interplay between NHEJ and other pathways for repair of IR-induced DNA damage. |
| Databáze: | OpenAIRE |
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