Sterically hindered phenols in negative ion mobility spectrometry-mass spectrometry
| Autor: | Jyrki Viidanoja, C. S. Pedersen, Jaakko Laakia, Alexey Adamov, Tapio Kotiaho, Alexey A. Sysoev |
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| Rok vydání: | 2009 |
| Předmět: |
Steric effects
010401 analytical chemistry Organic Chemistry Analytical chemistry chemistry.chemical_element Stereoisomerism Atmospheric-pressure chemical ionization 010402 general chemistry Mass spectrometry 01 natural sciences Oxygen 0104 chemical sciences Analytical Chemistry Ion Deprotonation Phenols chemistry Tandem Mass Spectrometry Mass spectrum Molecule Spectroscopy |
| Zdroj: | Rapid Communications in Mass Spectrometry. 23:3069-3076 |
| ISSN: | 1097-0231 0951-4198 |
| DOI: | 10.1002/rcm.4223 |
| Popis: | Negative corona discharge atmospheric pressure chemical ionization (APCI) was used to investigate phenols with varying numbers of tert-butyl groups using ion mobility spectrometry–mass spectrometry (IMS-MS). The main characteristic ion observed for all the phenolic compounds was the deprotonated molecule [M–H]−. 2-tert-Butylphenol showed one main mobility peak in the mass-selected mobility spectrum of the [M–H]− ion measured under nitrogen atmosphere. When air was used as a nebulizer gas an oxygen addition ion was seen in the mass spectrum and, interestingly, this new species [M–H+O]− had a shorter drift time than the lighter [M–H]− ion. Other phenolic compounds primarily produced two IMS peaks in the mass-selected mobility spectra measured using the [M–H]− ion. It was also observed that two isomeric compounds, 2,4-di-tert-butylphenol and 2,6-di-tert-butylphenol, could be separated with IMS. In addition, mobilities of various characteristic ions of 2,4,6-trinitrotoluene were measured, since this compound was previously used as a mobility standard. The possibility of using phenolic compounds as mobility standards is also discussed. Copyright © 2009 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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