Effect of aerobic exercise training dose on liver fat and visceral adiposity
| Autor: | James Gerofi, Jacob George, Daniel A. Hackett, Michael K. Baker, Ian D. Caterson, Vivienne Chuter, Helen M. Parker, Amanda Sainsbury, Nathan A. Johnson, Helen O'Connor, Shelley E. Keating |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adipose tissue Overweight Intra-Abdominal Fat chemistry.chemical_compound Weight loss Internal medicine Weight Loss medicine Aerobic exercise Humans Exercise physiology Exercise Rating of perceived exertion Hepatology Triglyceride business.industry Resistance Training Middle Aged Exercise Therapy Endocrinology Treatment Outcome chemistry Obesity Abdominal Female medicine.symptom business Body mass index Follow-Up Studies |
| Zdroj: | Journal of hepatology. 63(1) |
| ISSN: | 1600-0641 |
| Popis: | Background & Aims Aerobic exercise reduces liver fat and visceral adipose tissue (VAT). However, there is limited data from randomized trials to inform exercise programming recommendations. This study examined the efficacy of commonly prescribed exercise doses for reducing liver fat and VAT using a randomized placebo-controlled design. Methods Inactive and overweight/obese adults received 8weeks of either; i) low to moderate intensity, high volume aerobic exercise (LO:HI, 50% VO 2peak , 60min, 4d/week); ii) high intensity, low volume aerobic exercise (HI:LO, 70% VO 2peak , 45min, 3d/week); iii) low to moderate intensity, low volume aerobic exercise (LO:LO, 50% VO 2peak, 45min, 3d/week); or iv) placebo (PLA). Liver fat (spectroscopy) and VAT (magnetic resonance imaging) were measured before and after intervention. Results Forty-seven of the 48 (n=12 in each group) participants completed the trial. There were no serious adverse events. There was a significant change in group×time interaction in liver fat, which reduced in HI:LO by 2.38±0.73%, in LO:HI by 2.62±1.00%, and in LO:LO by 0.84±0.47% but not in PLA (increase of 1.10±0.62%) ( p =0.04). There was a significant reduction in VAT in HI:LO (−258.38±87.78cm 3 ), in LO:HI (−386.80±119.5cm 3 ), and in LO:LO (−212.96±105.54cm 3 ), but not in PLA (92.64±83.46cm 3 ) ( p =0.03). There were no significant differences between the dose or intensity of the exercise regimen and reductions in liver fat or VAT ( p >0.05). Conclusion The study found no difference in efficacy of liver fat reduction by either aerobic exercise dose or intensity. All of the aerobic exercise regimens employed reduced liver fat and VAT by a small amount without clinically significant weight loss. |
| Databáze: | OpenAIRE |
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