| Autor: |
Shuo Shi, Qiuping Zhang, Hao Sun, Zehui Su, Jie Dan, Yanmin Liang, Yi Kang, Ting Du, Jing Sun, Jianlong Wang, Wentao Zhang |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
ACS Biomaterials Science & Engineering. 8:5145-5154 |
| ISSN: |
2373-9878 |
| DOI: |
10.1021/acsbiomaterials.2c00985 |
| Popis: |
The high systemic blood glucose concentration of hyperglycemic wound microenvironment (WME) severely impedes the disinfection and healing of infected skin wounds. Herein, a WME-activated smart natural product, integrated GOx-GA-Fe nanozyme (GGFzyme), is engineered, which combines a nanozyme and natural enzyme to promote reactive oxygen species (ROS) generation in situ for hyperglycemic wound disinfection. GGFzyme can consume a high concentration of glucose in hyperglycemia wounds and generate H |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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