Infantile Pyknocytosis: An Uncommon Cause of Newborn Hemolytic Anemia

Autor: Tara E. Ness, Jayme Castillo, Parth S. Mehta
Rok vydání: 2020
Předmět:
Zdroj: Journal of Pediatric Hematology/Oncology. 42:e251-e253
ISSN: 1077-4114
DOI: 10.1097/mph.0000000000001461
Popis: Infantile pyknocytosis is a rare cause of neonatal hemolytic anemia, which presents in the first few weeks of life. We report a classic case of infantile pyknocytosis that presented to our institution with rebound hyperbilirubinemia after receiving phototherapy. The infant was found to have a hemoglobin of 5.8 g/dL, requiring a total of 15 mL/kg of red blood cells (in 2 separate transfusions) before discharge. The diagnosis was ultimately made by a review of the peripheral blood smear. We review the literature and suggest pediatricians consider infantile pyknocytosis on their differential when hemolytic anemia presents in the newborn period.
Databáze: OpenAIRE