Withanolides from aerial parts of Nicandra physalodes
| Autor: | Jie-Qing Liu, Gao-Ting Zhao, Xing-Rong Peng, Ming-Hua Qiu, Jin-Run Dong, Afsar Khan, Hai-Zhou Li, Mu-Yuan Yu, Lin Zhou |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Stereochemistry
Plant Science Horticulture 01 natural sciences Biochemistry Cell Line Tumor Humans Moiety Cytotoxicity Withanolides Molecular Biology Solanaceae chemistry.chemical_classification Molecular Structure biology Plant Extracts 010405 organic chemistry Aromatic amine General Medicine Plant Components Aerial biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Human cancer Nicandra |
| Zdroj: | Phytochemistry. 137:148-155 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/j.phytochem.2017.02.009 |
| Popis: | Twenty withanolides, including previously unknown nicanlodes A-M, were isolated from aerial parts of Nicandra physalodes. Their structural elucidations were unambiguously achieved through interpretation of extensive spectroscopic data (NMR and HRMS) and by comparison with literature data. Nicanlodes A and B have an unusual aromatic amine moiety. The isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines. |
| Databáze: | OpenAIRE |
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