Development and evaluation of microwave-assisted and ultrasound-assisted methods based on a quick, easy, cheap, effective, rugged, and safe sample preparation approach for the determination of bisphenol analogues in serum and sediments
| Autor: | Shanjun Song, Mingwu Shao, Feng Guo, Yajuan He, Weihua Wang, Huiyu Wang, Liliang Liu, Xinhua Dai |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Geologic Sediments Materials science Bisphenol Ethyl acetate Filtration and Separation 010501 environmental sciences 01 natural sciences Analytical Chemistry Rats Sprague-Dawley chemistry.chemical_compound Phenols Cyclohexanes Tandem Mass Spectrometry Animals Humans Ultrasonics Sample preparation Sulfones Solid phase extraction Benzhydryl Compounds Microwaves Chromatography High Pressure Liquid 0105 earth and related environmental sciences Detection limit Chromatography Solid Phase Extraction 010401 analytical chemistry Extraction (chemistry) Carbon black 0104 chemical sciences Hexane chemistry Solvents |
| Zdroj: | Journal of Separation Science. 40:4610-4618 |
| ISSN: | 1615-9306 |
| DOI: | 10.1002/jssc.201700628 |
| Popis: | Microwave- and ultrasound-assisted methods based on a quick, easy, cheap, effective, rugged, and safe sample preparation approach followed by high-performance liquid chromatography with tandem mass spectrometry were developed for the simultaneous determination of eight bisphenol analogues in serum and sediment. The developed methods provided satisfactory extraction efficiency for the energy provided by microwaves and ultrasound. Compositions of commercial sorbents (primary secondary amine, MgSO4 , octadecyl-modified silica, and graphitized carbon black) were evaluated. The ultrasound-assisted method was suited for serum using primary secondary amine, MgSO4 , and octadecyl-modified silica as sorbents and a mixture of hexane and ethyl acetate as extraction solvent. The microwave-assisted method worked better for sediment with tetrahydrofuran and methanol as solvents and primary secondary amine, MgSO4 , octadecyl-modified silica, and graphitized carbon black as sorbents. Other experimental parameters, such as extraction temperature and time, were also optimized. The inter- and intraday relative standard deviations ranged from 2.7 to 5.5%. The limits of detection were between 0.1 and 1.0 ng/mL for serum and between 0.1 and 0.5 ng/g dry weight for sediment. The proposed methods were successfully applied to seven sediment and 20 human serum samples. The results showed that the developed methods were practical for the analysis and biomonitoring of bisphenols in sera and sediment. |
| Databáze: | OpenAIRE |
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