Pancreatitis and altered glucose tolerance in mice infected with coxsackie B4 virus
| Autor: | Elizabeth R. Richens, Jack D. Davies, Martin Hartog |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Male
Endocrinology Diabetes and Metabolism CD1 Coxsackievirus Infections Spleen Biology Virus Mice Endocrinology Diabetes mellitus Internal Medicine medicine Animals Pancreas Enterovirus Coxsackie B4 virus General Medicine Glucose Tolerance Test medicine.disease biology.organism_classification Disease Models Animal medicine.anatomical_structure Diabetes Mellitus Type 1 Pancreatitis Immunology Infiltration (medical) |
| Zdroj: | Acta diabetologica latina. 14(3-4) |
| ISSN: | 0001-5563 |
| Popis: | CD1 mice infected with Coxsackie B4 virus showed an early polymorph infiltration of the pancreas, which later changed to a mononuclear exudate. A state of glucose intolerance developed concurrently and both events coincided with the inhibition of migration of spleen cells in the presence of the virus. The relevance of these findings to human juvenile-onset diabetes mellitus is discussed. |
| Databáze: | OpenAIRE |
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