The effects of septoplasty surgery on serum oxidative stress levels
| Autor: | Abdurrahman Yetiş, Duran Karataş, Müge Özcan, Adnan Ekinci, Emre Demir |
|---|---|
| Přispěvatelé: | Hitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Total Oxidant Status medicine.disease_cause Antioxidants 03 medical and health sciences Young Adult 0302 clinical medicine medicine Humans In patient Postoperative Period 030223 otorhinolaryngology Nasal Septum biology Septoplasty business.industry Aryldialkylphosphatase Paraoxonase Nose Deformities Acquired General Medicine Middle Aged Serum samples Oxidants Rhinoplasty PON1 Surgery Oxidative Stress Treatment Outcome Otorhinolaryngology Anesthesia Preoperative Period biology.protein Female Neurosurgery Nasal Obstruction Total Antioxidant Status business Oxidation-Reduction 030217 neurology & neurosurgery Oxidative stress Biomarkers |
| Popis: | The aim of this study is to compare the total antioxidant status (TAS), total oxidant status (TOS), and paraoxonase (PON1) serum levels in patients who have undergone septoplasty (NSD). Forty-six patients (mean age 33.7) aged between 18 and 50 years who were diagnosed with nasal septal deviation (NSD) were included in the study. The TAS, TOS, and PON1 levels were compared in the serum samples obtained 1 month before the septoplasty and 3 months after surgery. There was a significant increase in mean TAS after septoplasty (1.041 vs. 1.124 mmol/L, p = 0.011). The mean TOS decreased significantly after septoplasty (20.631 vs. 5.946 mmol/L, p = 0.011). The mean pre- and postoperative PON1 levels were similar (326.93 ± 215.22 vs. 275.20 ± 167.76 U/L, p = 0.253). Increased TAS and decreased TOS after septoplasty show that patients with NSD are under oxidative stress that is relieved following septoplasty. © 2017, Springer-Verlag Berlin Heidelberg. |
| Databáze: | OpenAIRE |
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