99Tcm-(tin) colloid scans in the evaluation of renal transplant rejection
| Autor: | H. J. Toh, A. S.W. Goh, F. X. Sundram, R. P.S. Edmondson, E. S. Ang |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Graft Rejection
business.industry Uptake ratio chemistry.chemical_element Technetium Tin Compounds General Medicine Normal values Kidney Kidney Transplantation Colloid Technetium Compounds chemistry Tin Medicine Renal transplant rejection Humans Radiology Nuclear Medicine and imaging Colloids Nuclear medicine business Radionuclide Imaging |
| Zdroj: | Nuclear medicine communications. 7(12) |
| ISSN: | 0143-3636 |
| Popis: | Technetium-99m-(tin) colloid uptake in renal transplants was quantified to evaluate rejection. A dynamic acquisition following i.v. injection of 110 MBq of this radiopharmaceutical enabled quantification of 15 to 20 min transplant uptake (PU), in terms of percentage of an injected dose after allowing for attenuation in the patient. An uptake ratio (UR) i.e. the ratio of 15 to 20 min uptake over the 0 to 5 min uptake was also derived. Normal values were obtained in 20 stable functioning transplants (normal PU less than or equal to 1%, normal UR less than or equal to 0.7). In 66 patients, PU and UR were compared with clinical, biochemical, histological and radiological, evidence of rejection. A sensitivity of 70% and specificity of 85% was obtained for this 99Tcm-(tin) colloid study in the diagnosis of renal transplant rejection. |
| Databáze: | OpenAIRE |
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