The Effect of either Aerobic Exercise Training or Chrysin Supplementation on Mitochondrial Biogenesis in Skeletal Muscle of High Fat Diet-Induced Obese Mice
| Autor: | Heegeun Park, Kwangmoo Lee, Sang-Min An, Kyung-Il Kim, Wang-Lok Lee |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
mitochondrial biogenesis lcsh:TX341-641 Physical Therapy Sports Therapy and Rehabilitation lcsh:Biochemistry chrysin chemistry.chemical_compound Physiology (medical) Internal medicine medicine Aerobic exercise lcsh:QD415-436 Chrysin skeletal muscle Obese Mice obese business.industry Public Health Environmental and Occupational Health Skeletal muscle High fat diet aerobic exercise medicine.anatomical_structure Endocrinology chemistry Mitochondrial biogenesis business lcsh:Nutrition. Foods and food supply |
| Zdroj: | 운동과학, Vol 28, Iss 4, Pp 365-372 (2019) |
| ISSN: | 2384-0544 1226-1726 |
| DOI: | 10.15857/ksep.2019.28.4.365 |
| Popis: | PURPOSE The purpose of this study was to investigate the effects of either aerobic exercise or resveratrol supplementation on mitochondrial biogenesis in skeletal muscle of the high fat diet-induced obese mice. METHODS C57BL/6 (4 weeks aged) male mice were divided into four groups; normal diet group (NC, n=10), high fat diet group (HC), high fat diet group with chrysin supplementation (HCh, n=10) and high fat diet with exercise group (HE, n=10). Aerobic exercise was performed on a treadmill exercise for 40-60 min/day at 10-14 m/min, 0% grade, 4 days/week for 16 weeks. Chrysin (50 mg/kg body weight) daily administrated orally at 4 days/week frequency for 16 weeks. RESULTS The gene expression of SIRT-3 in HE group was significantly increased compared to that in HC group (p |
| Databáze: | OpenAIRE |
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