Is ISABA-1customized forAcinetobacter?
| Autor: | Heidi Segal, Seike Garny, B. Gay Elisha |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Acinetobacter baumannii
Molecular Sequence Data Microbial Sensitivity Tests medicine.disease_cause Microbiology Enterobacteriaceae Transcription (biology) Drug Resistance Bacterial Genetics medicine Humans Cloning Molecular Insertion sequence Molecular Biology Gene Sulfonamides Acinetobacter Base Sequence biology Pseudomonas aeruginosa Promoter Sequence Analysis DNA biology.organism_classification Anti-Bacterial Agents DNA Transposable Elements Antibiotic resistance genes |
| Zdroj: | FEMS Microbiology Letters. 243:425-429 |
| ISSN: | 1574-6968 0378-1097 |
| DOI: | 10.1016/j.femsle.2005.01.005 |
| Popis: | An insertion sequence (IS(ABA-1)) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter baumannii strains, IS(ABA-1) was identified adjacent to sulII and transcription of the resistance gene is presumed to be dependent on promoter sequences within the IS. Since the IS is adjacent to ampC and bla(OXA) in this A. baumannii strain, it may be that IS(ABA-1) plays an important role in the expression of antibiotic resistance genes in this genus. |
| Databáze: | OpenAIRE |
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