Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing
| Autor: | Ingrid Banovic, Louise Montreuil, Marie Derrey-Bunel, Fabrizio Scrima, Guillaume Savoye, Laurent Beaugerie, Marie-Claire Gay |
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| Přispěvatelé: | Centre de Recherches sur les Fonctionnements et Dysfonctionnements Psychologiques (CRFDP), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut de Recherche Interdisciplinaire Homme et Société (IRIHS), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Groupe Hospitalier du Havre, Service d'Hépato-Gastroentérologie [CHU Rouen], Hôpital Charles Nicolle [Rouen]-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Clinique, Psychanalyse, Développement (CliPsyD), Université Paris Nanterre (UPN), Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2020 |
| Předmět: |
media_common.quotation_subject
lcsh:BF1-990 Disease Anger Emotional processing 050105 experimental psychology Disease activity 03 medical and health sciences 0302 clinical medicine medicine Psychology 0501 psychology and cognitive sciences General Psychology Depressive symptoms media_common emotional processing Crohn's disease Crohn disease anger 05 social sciences [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology Brief Research Report medicine.disease lcsh:Psychology depression Anxiety fatigue medicine.symptom disease activity 030217 neurology & neurosurgery Crohn’s Disease Clinical psychology |
| Zdroj: | Frontiers in Psychology Frontiers in Psychology, Frontiers, 2020, 11, ⟨10.3389/fpsyg.2020.00703⟩ Frontiers in Psychology, 2020, 11, ⟨10.3389/fpsyg.2020.00703⟩ Frontiers in Psychology, Vol 11 (2020) |
| ISSN: | 1664-1078 |
| Popis: | International audience; Because the relationship between Crohn’s Disease (CD) activity and CD-related fatigue remains poorly understood, this study investigated the role of underlying psychological processes (depression, anxiety, and emotional processing). It was expected that the relationship between CD activity and CD-related fatigue would be mediated by depression and anxiety and also by a deficit in emotional processing. This prediction was tested in 110 CD patients who completed self-reported questionnaires assessing fatigue (FSS), clinical activity of Crohn’s Disease (HBAI), psychological suffering (HADS), and emotional processing (EPS-25). A path analysis showed both direct and indirect effects in the relationship between CD activity and CD-related fatigue, accounting for 33% of the variance. One indirect effect on the experience of fatigue was depression, but there was no effect of anxiety. These preliminary results confirmed that disease activity induces an increase in depressive symptoms, which in turn leads to an increase in the level of fatigue. The most novel result of the present study is that emotional processing had an indirect effect on the relationship between CD and CD-related fatigue: when the disease was more active, patients exhibited greater disruption of emotional processing, which in turn led to greater fatigue. These results did not reveal any association between depression and emotional processing. In conclusion, this work highlights the role of emotional processing in CD-related fatigue and the importance of taking this factor into account in order to manage this condition better. |
| Databáze: | OpenAIRE |
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