Critical need for pharmacologic treatment options in NAFLD: A pediatric perspective

Autor: Chelsea Hosey-Cojocari, Chance S. Friesen, Valentina Shakhnovich, Jonathan B. Wagner, Iván L. Csanaky, Sherwin S Chan
Rok vydání: 2021
Předmět:
Zdroj: Clinical and Translational Science, Vol 14, Iss 3, Pp 781-783 (2021)
Clinical and Translational Science
ISSN: 1752-8062
1752-8054
DOI: 10.1111/cts.12952
Popis: Nonalcoholic fatty liver disease (NAFLD) affects up to 70% of children with obesity and has become the number one etiology for liver transplant in the United States. Early, effective intervention is critical to prevent disease progression into adulthood. Yet, it is seldom achieved through lifestyle modification alone. Thus, children must be included in NAFLD pharmacology trials, which, to date, continue to focus primarily on adult populations. This commentary serves as a call to action.
Databáze: OpenAIRE