RIght VErsus Left Apical transvenous pacing for bradycardia: Results of the RIVELA randomized study

Autor: Hajo Müller, Richard Kobza, Catherine Klersy, Carine Stettler, Frits W. Prinzen, Angelo Auricchio, Christian Sticherling, Peter Ammann, Heiko Zerlik, Haran Burri
Přispěvatelé: University of Zurich, Burri, Haran
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Bradycardia
Cardiac function curve
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty
medicine.medical_treatment
610 Medicine & health
Ventricular pacing
Coronary sinus
030204 cardiovascular system & hematology
Prosthesis
11171 Cardiocentro Ticino
2705 Cardiology and Cardiovascular Medicine
03 medical and health sciences
0302 clinical medicine
2737 Physiology (medical)
Physiology (medical)
Internal medicine
medicine
Clinical endpoint
030212 general & internal medicine
cardiovascular diseases
Ventricular function
ddc:616
Tricuspid valve
Ejection fraction
business.industry
Left ventricle
Transvenous pacing
medicine.anatomical_structure
lcsh:RC666-701
Anesthesia
Cardiology
cardiovascular system
Right ventricle
Original Article
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Zdroj: Indian Pacing and Electrophysiology Journal
Indian Pacing and Electrophysiology Journal, Vol. 17, No 6 (2017) pp. 171-175
Indian Pacing and Electrophysiology Journal, Vol 17, Iss 6, Pp 171-175 (2017)
ISSN: 0972-6292
DOI: 10.5167/uzh-145197
Popis: Aims: To compare cardiac function when pacing from the right or left ventricular apex in patients with preserved left ventricular systolic function, at 1-year follow-up. Methods: Prospective, multicentre centre randomizing conventional right ventricular apical (RVA) versus left ventricular apical (LVA) pacing using a coronary sinus lead in patients requiring ventricular pacing for bradycardia. Follow-up was performed using 3D-echocardiography at 6 and 12 months. Results: A total of 36 patients (age 75.4 ± 8.7 years, 21 males) were enrolled (17 patients in the RVA group and 19 patients in the LVA group). A right ventricular lead was implanted in 8 patients in the LVA group, mainly because of high capture thresholds. There were no differences in the primary endpoint of LVEF at 1 year (60.4 ± 7.1% vs 62.1 ± 7.2% for the RVA and LVA groups respectively, P = 0.26) nor in any of the secondary endpoints (left ventricular dimensions, left ventricular diastolic function, right ventricular systolic function and tricuspid/mitral insufficiency). LVEF did not change significantly over follow-up in either group. Capture thresholds were significantly higher in the LVA group, and two patients had unexpected loss of capture of the coronary sinus lead during follow-up. Conclusions: Left univentricular pacing seems to be comparable to conventional RVA pacing in terms of ventricular function at up to 1 year follow-up, and is an option to consider in selected patients (e.g. those with a tricuspid valve prosthesis). Keywords: Ventricular pacing, Right ventricle, Left ventricle, Coronary sinus, Ventricular function
Databáze: OpenAIRE