Extensive tracheal resection in lung cancer and tuberculosis: a case report
| Autor: | Gjumrakch Aliev, Liliya V. Gavryushova, D.B. Giller, Galina V. Scherbakova, Siva G Somasundaram, Liudmila M. Mikhaleva, Vladimir N. Nikolenko, Elizaveta V Mikhaylenko, B.D. Giller, Cecil E Kirkland |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Tuberculosis Lung Neoplasms Time Factors medicine.medical_treatment Bronchoconstriction Case Report 03 medical and health sciences Pneumonectomy 0302 clinical medicine medicine Carcinoma Humans 030212 general & internal medicine Lung cancer Tuberculosis Pulmonary lcsh:RC705-779 Bronchus business.industry Cancer lcsh:Diseases of the respiratory system Chemoradiotherapy respiratory system Middle Aged medicine.disease Radiation therapy Trachea medicine.anatomical_structure Treatment Outcome 030228 respiratory system Tracheal bifurcation resection Carcinoma Squamous Cell Radiology Airway obstruction Neoplasm Recurrence Local business |
| Zdroj: | BMC Pulmonary Medicine BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-5 (2020) |
| ISSN: | 1471-2466 |
| Popis: | Background Tracheal bifurcation resection remains the greatest challenge in airway reconstruction, especially with extensive lesions. Additionally, lung cancer and pulmonary tuberculosis comorbidity complicate the chemoradiotherapy treatment due to the TB reactivation. This case describes tracheal resection in a patient with both tuberculosis (TB) and lung cancer. Case presentation The patient was diagnosed with right lung tuberculosis and upper lobe cancer with trachea invasion complicated by hemoptysis. A right pneumonectomy with circular trachea bifurcation resection was performed. Radiotherapy and chemotherapy were not administered to avoid TB reactivation. At 5.5 years post-surgery, there was cancer recurrence that was treated with radiation therapy. At 10 years post-surgery, an invasive squamous-cell carcinoma of a three-segment bronchus on the left was revealed. Radiation therapy and a course of chemotherapy were carried out with almost complete tumor regression. Conclusions TB presence should not serve as a basis for the refusal of cancer treatment. Combined treatment may be recommended when the main infection focus in the pulmonary parenchyma is removed during surgery. |
| Databáze: | OpenAIRE |
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