Clinicopathological evaluation of 15 Ectopic adrenal tissues
| Autor: | Aylin Ege Gul, Sevinç Hallaç Keser, Nagehan Ozdemir Barisik, Sibel Sensu, Yeşim Gürbüz |
|---|---|
| Přispěvatelé: | İstinye Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Sibel Şensu / 0000-0002-4607-780X, Yeşim Gürbüz / 0000-0002-4278-8241, Şensu, Sibel, Gürbüz, Yeşim Saliha, Sibel Şensu / AGU-9782-2022, Yeşim Gürbüz / CRQ-9252-2022, Sibel Şensu / 35746731800, Yeşim Gürbüz / 7004052030 |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Ovarian Neoplasms Pathology medicine.medical_specialty Ovarian serous cystadenoma Adrenal cortex Serous cystadenocarcinoma business.industry General Medicine Seminoma Ovarian Tumor Choristoma medicine.disease Serous Cystadenoma Clear Cell Tumors Metastasis Ovarian tumor medicine.anatomical_structure Ectopic Adrenal Testicular Neoplasms medicine Humans Female Germ cell tumors business |
| Popis: | Background: Ectopic adrenal tissue is a rare condition associated with embryological development defects seen in many different areas in the abdomen and pelvis. Here, we aimed to discuss the clinicopathological features of ectopic adrenal tissues diagnosed in our clinic, in light of the literature. Methods: We included cases of ectopic adrenal tissues incidentally detected in the specimens from patients undergoing operation for various diagnoses during 2012- March 2020. The cases were examined according to gender, age, location and accompanying pathological diagnoses. During this period, 15 cases of ectopic adrenal tissues (6 paratubal, 3 paraovarian, 2 paratesticular, 1 spermatic cord, 1 paraaortic, 1 liver capsule, 1 omentum) were detected accompanied by two endometrial carcinomas, two serous cystadenomas, one seminoma, one mixed germ cell tumor, one bilateral ovarian serous carcinoma and hepatic high-grade colon adenocarcinoma metastasis. Results: In this report, the fifth ectopic adrenal tissue accompanying a malignant testicular tumor, the fifth and sixth ectopic adrenal tissues occurring with ovarian serous cystadenoma, the first case observed with serous cystadenocarcinoma and the first case detected with hepatic adenocarcinoma metastasis are presented. Our cases are mostly women and adult men. Conclusion: Ectopic adrenal tissues can lead to hormonal problems and also to adrenal cortex and medulla neoplasms. Microscopically, they may be confused with clear cell gynecological and germ cell tumors. If the ectopic focus is misdiagnosed as an implant, a benign entity may be incorrectly reported as malignant. Also, it is important to prevent mis-staging in malignancies. For precise diagnosis, an immunopanel such as inhibin, melan A, and calretinin can be performed. WOS:000674176500005 34196190 Q3 |
| Databáze: | OpenAIRE |
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